Vaccine Requirements for

Officers in the Commissioned Corps 

(Additional Information is available in the Immunization Guide)


Vaccine Dose Required Schedule Contraindications* Notes
Hepatitis A (HAV)

1.0 mL IM Two doses recommended at 6-12 months apart. OR

Positive titer

Anaphylactic reactions to alum or the preservative 2-phenoxyethanol. Twinrix is a combined Hep A and Hep B vaccination and is administered in 3 vaccinations at 0,1,6 months
Hepatitis B (HBV)

0.5 mL IM Three doses recommended at:

0, 1 and 6 months. 


Positive titer

Anaphylactic reaction to baker’s yeast.

Pregnancy should not be considered a contraindication to vaccination of women.

Confirmation of positive titer 1-2 months after completion of the 3-dose series.

Twinrix is a combined Hep A and Hep B vaccination and is administered in 3 vaccinations at 0,1,6 months


0.5 mL IM Annually (fall) with current vaccine. Allergy to egg  
Measles, Mumps and Rubella (MMR)

0.5 mL SQ Completion of basic two dose series.


Positive titers for Measles, Mumps and Rubella

See note.

Pregnancy. Anaphylactic reactions to neomycin or gelatin. Known immunodeficiency. Regardless of age, all Health Care Workers (HCWs) are recommended to have two doses unless they can produce laboratory evidence of immunity.(i.e., positive titers for Measles, Mumps, AND Rubella)
Poliovirus (IPV)

0.5 mL SC or IM Completion of basic childhood series. 
One single lifetime "booster" dose as an adult (>18 y.o.).
Anaphylactic reaction to neomycin, polymycin B or streptomycin. Only the injectable form is available.

Polio titers are NOT acceptable (per CDC guidance)

Tetanus-diptheria (Td)

0.5 mL IM Completion of basic three dose series.

Booster every 10 years.

Neurological reactions following a prior dose. Previous episode of Guillan-Barre syndrome (GBS) occurring within 6 weeks of vaccination.  

0.5 mL SC Two doses 4-8 weeks apart.

Completion of basic series OR medical documentation of chickenpox illness  OR  positive titer.

Pregnancy. Anaphylactic reaction to neomycin and gelatin. Infection with HIV.

Known immunodeficiency.

Serologic screening should be done for HCWs who have not received the vaccination series.
Tuberculin Skin Test (PPD)

0.1mL ID Annually.   Three month post-exposure testing after deployment if known TB exposure.

*General Contraindications:

  • Anaphylactic reaction to a vaccine / vaccine constituent contraindicates further doses of that vaccine.
  • Moderate or severe illness with or without a fever requires deferral to a later date.
  • Vaccination of pregnant women should be undertaken in consultation with her healthcare provider.

Routine immunization for typhoid is not recommended for sanitation workers or persons living in areas in which natural disasters (e.g., floods) have occurred. Vaccination is indicted only for persons living in typhoid-endemic areas.


Back to Home Page Questions or problems regarding this web site can be emailed directly to the WebMaster
Notice: This Government Computer System is provided as a public service by the
Office of the Surgeon General, Department of Health and Human Services.
Any unauthorized use of this service may be punishable under the
Computer Fraud and Abuse Act of 1986.
This page was last modified: 11/17/2011 02:31 PM